PPBP Polyclonal Antibody (CAB24514)
- SKU:
- CAB24514
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | PPBP Polyclonal Antibody |
| Product Code: | CAB24514 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293T-PPBP5-His(C) |
| Cellular Location: | Secreted |
The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 59-128 of human PPBP (NP_002695.1). |
| Sequence: | AELRC MCIKT TSGIH PKNIQ SLEVI GKGTH CNQVE VIATL KDGRK ICLDP DAPRI KKIVQ KKLAG DESAD |
| Synonyms: | PPBP, B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1, platelet basic protein |
| Calculated MW: | 13kDa |
| Observed MW: | 11kDa/14kDa |
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