POLR2A (N-terminal) Monoclonal Antibody
- SKU:
- CAB21980
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IP
Description
| Product Name: | POLR2A (N-terminal) Monoclonal Antibody |
| Product Code: | CAB21980 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54153 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IP, ChIP, ELISA |
| Key Applications: | Western blotting, Immunoprecipitation |
| Recommended Dilution: | WB 1:1000-1:5000, IP 1:1000-1:5000, ChIP 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse thymus |
| Cellular Location: | Nucleus |
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 550-650 of human POLR2A POLR2A (N-terminal) (NP_000928.1). |
| Sequence: | KRDVF LERGE VMNLL MFLST WDGKV PQPAI LKPRP LWTGK QIFSL IIPGH INCIR THSTH PDDED SGPYK HISPG DTKVV VENGE LIMGI LCKKS LGTSA G |
| Synonyms: | RPB1, RPO2, POLR2, POLRA, RPBh1, RPOL2, NEDHIB, RpIILS, hsRPB1, hRPB220 |
| Calculated MW: | 217kDa |
| Observed MW: | 250kDa |
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