Description
| Antibody Name: | POLR1D Antibody (PACO43637) |
| Antibody SKU: | PACO43637 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human DNA-directed RNA polymerases I and III subunit RPAC2 protein (1-133AA) |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human skin tissue using PACO43637 at dilution of 1:100. |
| Background: | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. |
| Synonyms: | DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) (RNA polymerase I 16 kDa subunit) (RPA16) (RPC16) (hRPA19), POLR1D |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011] |
| UniProt Code: | P0DPB6 |
| NCBI GenInfo Identifier: | 11387119 |
| NCBI Gene ID: | 51082 |
| NCBI Accession: | Q9Y2S0.1 |
| UniProt Secondary Accession: | P0DPB6 |
| UniProt Related Accession: | P0DPB6,P0DPB5, P0DPB6 |
| Molecular Weight: | 14 |
| NCBI Full Name: | |
| NCBI Synonym Full Names: | RNA polymerase I and III subunit D |
| NCBI Official Symbol: | POLR1D |
| NCBI Official Synonym Symbols: | AC19; RPA9; TCS2; RPA16; RPAC2; RPC16; POLR1C; RPO1-3 |
| NCBI Protein Information: | DNA-directed RNA polymerases I and III subunit RPAC2; Protein POLR1D |
| UniProt Protein Name: | |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | |
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