Description
Antibody Name: | POLR1D Antibody (PACO43636) |
Antibody SKU: | PACO43636 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human DNA-directed RNA polymerases I and III subunit RPAC2 protein (1-133AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: DNA-directed RNA polymerases I and III subunit RPAC2 antibody at 10µg/ml + Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 16, 15 kDa. Observed band size: 16 kDa. | |
Immunohistochemistry of paraffin-embedded human liver tissue using PACO43636 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human skin tissue using PACO43636 at dilution of 1:100. |
Background: | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. |
Synonyms: | DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) (RNA polymerase I 16 kDa subunit) (RPA16) (RPC16) (hRPA19), POLR1D |
UniProt Protein Function: | |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011] |
UniProt Code: | P0DPB6 |
NCBI GenInfo Identifier: | 11387119 |
NCBI Gene ID: | 51082 |
NCBI Accession: | Q9Y2S0.1 |
UniProt Secondary Accession: | P0DPB6 |
UniProt Related Accession: | P0DPB6,P0DPB5, P0DPB6 |
Molecular Weight: | 14 |
NCBI Full Name: | |
NCBI Synonym Full Names: | RNA polymerase I and III subunit D |
NCBI Official Symbol: | POLR1D |
NCBI Official Synonym Symbols: | AC19; RPA9; TCS2; RPA16; RPAC2; RPC16; POLR1C; RPO1-3 |
NCBI Protein Information: | DNA-directed RNA polymerases I and III subunit RPAC2; Protein POLR1D |
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