POGZ Antibody (PACO29046)
- SKU:
- PACO29046
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | POGZ Antibody (PACO29046) |
| Antibody SKU: | PACO29046 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Pogo transposable element with ZNF domain protein (1-300AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human prostate cancer using PACO29046 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO29046 at dilution of 1:100. |
| Background: | Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms. |
| Synonyms: | Pogo transposable element with ZNF domain (Suppressor of hairy wing homolog 5) (Zinc finger protein 280E) (Zinc finger protein 635), POGZ, KIAA0461 SUHW5 ZNF280E ZNF635 |
| UniProt Protein Function: | POGZ: a transposable element with a zinc-finger (ZNF) domain. Interacts with the Sp1 transcription factor (SP1). Four alternatively spliced isoforms have been described.Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factorChromosomal Location of Human Ortholog: 1q21.3Cellular Component: cytoplasm; cytosol; nuclear chromatin; nucleoplasm; nucleusMolecular Function: DNA binding; metal ion binding; protein bindingBiological Process: cell division; kinetochore assembly; mitotic sister chromatid cohesionDisease: Mental Retardation, Autosomal Dominant 37 |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene appears to be a zinc finger protein containing a transposase domain at the C-terminus. This protein was found to interact with the transcription factor SP1 in a yeast two-hybrid system. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2010] |
| UniProt Code: | Q7Z3K3 |
| NCBI GenInfo Identifier: | 46397390 |
| NCBI Gene ID: | 23126 |
| NCBI Accession: | NP_055915 |
| UniProt Secondary Accession: | Q7Z3K3 |
| UniProt Related Accession: | Q7Z3K3 |
| Molecular Weight: | 155kDa |
| NCBI Full Name: | pogo transposable element with ZNF domain isoform 1 |
| NCBI Synonym Full Names: | pogo transposable element derived with ZNF domain |
| NCBI Official Symbol: | POGZ |
| NCBI Official Synonym Symbols: | MRD37; WHSUS; ZNF635; ZNF280E; ZNF635m |
| NCBI Protein Information: | pogo transposable element with ZNF domain |
| UniProt Protein Name: | Pogo transposable element with ZNF domain |
| UniProt Synonym Protein Names: | Suppressor of hairy wing homolog 5; Zinc finger protein 280E; Zinc finger protein 635 |
| Protein Family: | Pogo transposable element with ZNF domain |
| UniProt Gene Name: | POGZ |
| UniProt Entry Name: |
Related Products
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost
eutC Antibody
Overview Product Name:eutC AntibodyProduct Code:PACO64709Size:50µLTarget Names:eutCSpecies Reactivity:Escherichia coli
EPHA10 Antibody
Overview Product Name:EPHA10 AntibodyProduct Code:PACO64693Size:50µLTarget Names:EPHA10Species Reactivity:HumanH
otsB Antibody
Overview Product Name:otsB AntibodyProduct Code:PACO64885Size:50µLTarget Names:otsBSpecies Reactivity:Escherichia coli
PCDHA8 Antibody
Overview Product Name:PCDHA8 AntibodyProduct Code:PACO64893Size:50µLTarget Names:PCDHA8Species Reactivity:HumanH