Description
| Antibody Name: | PODXL2 Antibody (PACO11336) |
| Antibody SKU: | PACO11336 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human PODXL2 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | podocalyxin-like 2;PODXL2;PODLX2 ;Endoglycan; |
| UniProt Protein Function: | PODXL2: Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L- selectins. Belongs to the podocalyxin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Cell adhesionChromosomal Location of Human Ortholog: 3q21.3Cellular Component: integral to plasma membraneMolecular Function: glycosaminoglycan binding; protein bindingBiological Process: leukocyte tethering or rolling |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the CD34 family of cell surface transmembrane proteins, which are characterized by an N-terminal extracellular mucin domain, globular and stalk domains, a single pass transmembrane region, and a charged cytoplasmic tail. The encoded protein is a ligand for vascular selectins. [provided by RefSeq, Oct 2012] |
| UniProt Code: | Q9NZ53 |
| NCBI GenInfo Identifier: | 74734719 |
| NCBI Gene ID: | 50512 |
| NCBI Accession: | Q9NZ53.1 |
| UniProt Secondary Accession: | Q9NZ53,Q6UVY4, Q8WUV6 |
| UniProt Related Accession: | Q9NZ53 |
| Molecular Weight: | 56,635 Da |
| NCBI Full Name: | Podocalyxin-like protein 2 |
| NCBI Synonym Full Names: | podocalyxin like 2 |
| NCBI Official Symbol: | PODXL2 |
| NCBI Official Synonym Symbols: | EG; PODLX2 |
| NCBI Protein Information: | podocalyxin-like protein 2 |
| UniProt Protein Name: | Podocalyxin-like protein 2 |
| UniProt Synonym Protein Names: | Endoglycan |
| Protein Family: | Podocalyxin-like protein |
| UniProt Gene Name: | PODXL2 |
| UniProt Entry Name: | PDXL2_HUMAN |