PMM1 Antibody (PACO11317)
- SKU:
- PACO11317
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PMM1 Antibody (PACO11317) |
| Antibody SKU: | PACO11317 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human PMM1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | phosphomannomutase 1;PMM1;Sec53 ; |
| UniProt Protein Function: | PMM1: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain. Belongs to the eukaryotic PMM family.Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; Carbohydrate Metabolism - fructose and mannose; EC 5.4.2.8; IsomeraseChromosomal Location of Human Ortholog: 22q13.2Cellular Component: cytosolMolecular Function: phosphomannomutase activity; protein bindingBiological Process: GDP-mannose biosynthetic process; mannose metabolic process; protein amino acid N-linked glycosylation; protein targeting to ER |
| UniProt Protein Details: | |
| NCBI Summary: | Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q92871 |
| NCBI GenInfo Identifier: | 194097356 |
| NCBI Gene ID: | 5372 |
| NCBI Accession: | NP_002667.2 |
| UniProt Secondary Accession: | Q92871,Q92586, A8K003 |
| UniProt Related Accession: | Q92871 |
| Molecular Weight: | 29,747 Da |
| NCBI Full Name: | phosphomannomutase 1 |
| NCBI Synonym Full Names: | phosphomannomutase 1 |
| NCBI Official Symbol: | PMM1 |
| NCBI Official Synonym Symbols: | Sec53 |
| NCBI Protein Information: | phosphomannomutase 1 |
| UniProt Protein Name: | Phosphomannomutase 1 |
| UniProt Synonym Protein Names: | PMMH-22 |
| Protein Family: | |
| UniProt Gene Name: | PMM1 |
| UniProt Entry Name: | PMM1_HUMAN |
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