ply Antibody (PACO34102)
- SKU:
- PACO34102
- Product Type:
- Antibody
- Reactivity:
- Bacteria - Streptococcus
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ply Antibody (PACO34102) |
| Antibody SKU: | PACO34102 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Streptococcus pneumoniae serotype 4 |
| Immunogen: | Recombinant Streptococcus pneumoniae serotype 4 Pneumolysin protein (2-471AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity). |
| Synonyms: | Pneumolysin (Thiol-activated cytolysin), ply |
| UniProt Protein Function: | Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P0C2J9 |
| NCBI GenInfo Identifier: | 447207105 |
| NCBI Gene ID: | |
| NCBI Accession: | WP_001284361.1 |
| UniProt Secondary Accession: | P0C2J9,P11990 |
| UniProt Related Accession: | P0C2J9 |
| Molecular Weight: | 54.8 kDa |
| NCBI Full Name: | pneumolysin |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Pneumolysin |
| UniProt Synonym Protein Names: | Thiol-activated cytolysin |
| Protein Family: | Pneumolysin |
| UniProt Gene Name: | ply |
| UniProt Entry Name: | TACY_STRPN |
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