PLS3 Polyclonal Antibody
- SKU:
- CAB21546
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IP
Description
| Product Name: | PLS3 Polyclonal Antibody |
| Product Code: | CAB21546 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, IP, ELISA |
| Key Applications: | Western blotting, Immunoprecipitation |
| Recommended Dilution: | WB 1:500-1:2000, IP 50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm |
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PLS3 (NP_005023.2). |
| Sequence: | MDEMA TTQIS KDELD ELKEA FAKVD LNSNG FICDY ELHEL FKEAN MPLPG YKVRE IIQKL MLDGD RNKDG KISFD EFVYI FQEVK SSDIA KTFRK AINRK EGICA LGGTS ELSSE GTQHS YSEEE KYAFV NWINK ALEND PDCRH VIPMN PNTDD LFKAV GDGIV LCKMI NLSVP DTIDE RAINK KKLTP FIIQE NLNLA LNSAS AIGCH VVNIG AEDLR AGKPH LVLGL LWQII KIGLF |
| Synonyms: | BMND18, T-plastin |
| Calculated MW: | 71kDa |
| Observed MW: | Refer to figures |
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