PLGRKT Antibody (PACO41358)
- SKU:
- PACO41358
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PLGRKT Antibody (PACO41358) |
| Antibody SKU: | PACO41358 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Plasminogen receptor (KT) protein (1-147AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: PLGRKT antibody at 6µg/ml. Lane 1: A431 whole cell lysate. Lane 2: Mouse lung tissue. Lane 3: NIH/3T3 whole cell lysate. Lane 4: U251 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 18 kDa. Observed band size: 18 kDa. |
 | Immunohistochemistry of paraffin-embedded human skin tissue using PACO41358 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO41358 at dilution of 1:100. |
| Background: | Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metallproteinase activation, such as of MMP2 and MMP9. |
| Synonyms: | Plasminogen receptor (KT) (Plg-R(KT)), PLGRKT, C9orf46 |
| UniProt Protein Function: | PLGRKT: Receptor for plasminogen. Regulates urokinase plasminogen activator-dependent and stimulates tissue-type plasminogen activator-dependent cell surface plasminogen activation. Proposed to be part of a local catecholaminergic cell plasminogen activation system that regulates neuroendocrine prohormone processing. Involved in regulation of inflammatory response; regulates monocyte chemotactic migration and matrix metallproteinase activation, such as of MMP2 and MMP9.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 9p24.1Cellular Component: integral to plasma membrane; mitochondrionMolecular Function: protein bindingBiological Process: chemotaxis; inflammatory response |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9HBL7 |
| NCBI GenInfo Identifier: | 332635095 |
| NCBI Gene ID: | 55848 |
| NCBI Accession: | NP_060935.2 |
| UniProt Secondary Accession: | Q9HBL7,Q9NZ44, B2R6W0 |
| UniProt Related Accession: | Q9HBL7 |
| Molecular Weight: | 17,201 Da |
| NCBI Full Name: | plasminogen receptor (KT) |
| NCBI Synonym Full Names: | plasminogen receptor, C-terminal lysine transmembrane protein |
| NCBI Official Symbol: | PLGRKT |
| NCBI Official Synonym Symbols: | AD025; MDS030; C9orf46; PLG-RKT; Plg-R(KT) |
| NCBI Protein Information: | plasminogen receptor (KT) |
| UniProt Protein Name: | Plasminogen receptor (KT) |
| UniProt Synonym Protein Names: | |
| Protein Family: | Plasminogen receptor |
| UniProt Gene Name: | PLGRKT |
| UniProt Entry Name: | PLRKT_HUMAN |
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