PLEKHF1 Antibody (PACO11299)
- SKU:
- PACO11299
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PLEKHF1 Antibody (PACO11299) |
| Antibody SKU: | PACO11299 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human PLEKHF1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | pleckstrin homology domain containing, family F (with FYVE domain) member 1;PLEKHF1;APPD;MGC4090;PHAFIN1;ZFYVE15 ; |
| UniProt Protein Function: | PKHF1: May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase- independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.Chromosomal Location of Human Ortholog: 19q12Cellular Component: endosome; endosome membrane; lysosomal membrane; lysosomeMolecular Function: phosphatidylinositol 3-phosphate binding; phosphatidylinositol-5-phosphate binding; protein bindingBiological Process: endosome organization and biogenesis; positive regulation of autophagy; vesicle organization and biogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96S99 |
| NCBI GenInfo Identifier: | 115502559 |
| NCBI Gene ID: | 79156 |
| NCBI Accession: | Q96S99.3 |
| UniProt Secondary Accession: | Q96S99,Q96K11, Q9BUB9 |
| UniProt Related Accession: | Q96S99 |
| Molecular Weight: | 31,195 Da |
| NCBI Full Name: | Pleckstrin homology domain-containing family F member 1 |
| NCBI Synonym Full Names: | pleckstrin homology and FYVE domain containing 1 |
| NCBI Official Symbol: | PLEKHF1 |
| NCBI Official Synonym Symbols: | APPD; LAPF; PHAFIN1; ZFYVE15 |
| NCBI Protein Information: | pleckstrin homology domain-containing family F member 1 |
| UniProt Protein Name: | Pleckstrin homology domain-containing family F member 1 |
| UniProt Synonym Protein Names: | Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains; Apoptosis-inducing protein; PH and FYVE domain-containing protein 1; Phafin-1; Zinc finger FYVE domain-containing protein 15 |
| Protein Family: | Pleckstrin homology domain-containing family |
| UniProt Gene Name: | PLEKHF1 |
| UniProt Entry Name: | PKHF1_HUMAN |
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