PLEKHA8 Antibody (PACO11297)
- SKU:
- PACO11297
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PLEKHA8 Antibody (PACO11297) |
| Antibody SKU: | PACO11297 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human PLEKHA8 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8;PLEKHA8;FAPP2;MGC3358 ; |
| UniProt Protein Function: | PLEKHA8: Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans- Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 7p14.3Cellular Component: trans-Golgi networkMolecular Function: glycolipid binding; glycolipid transporter activityBiological Process: lipid transport |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96JA3 |
| NCBI GenInfo Identifier: | 387912902 |
| NCBI Gene ID: | 84725 |
| NCBI Accession: | Q96JA3.3 |
| UniProt Secondary Accession: | Q96JA3,Q7Z5V8, Q9BU78, Q9H274, Q9H8Z7, B4DH00 |
| UniProt Related Accession: | Q96JA3 |
| Molecular Weight: | 49,462 Da |
| NCBI Full Name: | Pleckstrin homology domain-containing family A member 8 |
| NCBI Synonym Full Names: | pleckstrin homology domain containing A8 |
| NCBI Official Symbol: | PLEKHA8 |
| NCBI Official Synonym Symbols: | FAPP2 |
| NCBI Protein Information: | pleckstrin homology domain-containing family A member 8 |
| UniProt Protein Name: | Pleckstrin homology domain-containing family A member 8 |
| UniProt Synonym Protein Names: | Phosphatidylinositol-four-phosphate adapter protein 2; FAPP-2; Phosphoinositol 4-phosphate adapter protein 2; hFAPP2; Serologically defined breast cancer antigen NY-BR-86 |
| Protein Family: | Pleckstrin homology domain-containing family |
| UniProt Gene Name: | PLEKHA8 |
| UniProt Entry Name: | PKHA8_HUMAN |
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