PLCB2 Monoclonal Antibody
- SKU:
- CAB22526
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | PLCB2 Monoclonal Antibody |
| Product Code: | CAB22526 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55276 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HEL, Mouse thymus |
| Cellular Location: | cytosol, G-protein beta/gamma-subunit complex, Golgi apparatus, neuronal dense core vesicle, plasma membrane |
The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to the second messengers inositol 1, 4, 5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-199 of human PLCB2 (NP_004564.2). |
| Sequence: | MSLLN PVLLP PKVKA YLSQG ERFIK WDDET TVASP VILRV DPKGY YLYWT YQSKE MEFLD ITSIR DTRFG KFAKM PKSQK LRDVF NMDFP DNSFL LKTLT VVSGP DMVDL TFHNF VSYKE NVGKA WAEDV LALVK HPLTA NASRS TFLDK ILVKL KMQLN SEGKI PVKNF FQMFP ADRKR VEAAL SACHL PKGKN DAIN |
| Synonyms: | PLC-beta-2 |
| Calculated MW: | 134kDa |
| Observed MW: | 150kDa |
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