PLA2G4F Antibody (PACO11281)
- SKU:
- PACO11281
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PLA2G4F Antibody (PACO11281) |
| Antibody SKU: | PACO11281 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human PLA2G4F |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | phospholipase A2, group IVF;PLA2G4F;DKFZp666G192;DKFZp781B229;PLA2G4F/Z ;cPLA2-zeta |
| UniProt Protein Function: | PLA2G4F: a calcium-dependent phospholipase A2 that catalyzes the release of arachidonic acid from membrane phospholipids. Selectively hydrolyzes glycerophospholipids in the sn-2 position. Has higher enzyme activity for phosphatidylethanolamine than phosphatidylcholine. Has a much higher lysophospholipase and PLA(2) activity than PLA2G4B. Potently inhibited by pyrrolidine-2 and Wyeth-1. Its specific activity, inhibitor sensitivity, and low micromolar calcium dependence are similar to PLA2G4A. Translocates to ruffles and dynamic vesicular structures in a calcium-dependent manner. The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca2+ Three isoforms of the human protein are produced by alternative splicing.Protein type: Lipid Metabolism - arachidonic acid; EC 3.1.1.4; PhospholipaseChromosomal Location of Human Ortholog: 15q15.1Cellular Component: cytosolMolecular Function: lysophospholipase activity; phospholipase A1 activity; phospholipase A2 activityBiological Process: phospholipid metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q68DD2 |
| NCBI GenInfo Identifier: | 317373489 |
| NCBI Gene ID: | 255189 |
| NCBI Accession: | Q68DD2.3 |
| UniProt Secondary Accession: | Q68DD2,Q6ZMC8 |
| UniProt Related Accession: | Q68DD2 |
| Molecular Weight: | 95,310 Da |
| NCBI Full Name: | Cytosolic phospholipase A2 zeta |
| NCBI Synonym Full Names: | phospholipase A2 group IVF |
| NCBI Official Symbol: | PLA2G4F |
| NCBI Official Synonym Symbols: | PLA2G4FZ |
| NCBI Protein Information: | cytosolic phospholipase A2 zeta |
| UniProt Protein Name: | Cytosolic phospholipase A2 zeta |
| UniProt Synonym Protein Names: | Phospholipase A2 group IVF |
| Protein Family: | Cytosolic phospholipase |
| UniProt Gene Name: | PLA2G4F |
| UniProt Entry Name: | PA24F_HUMAN |
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