PKR/EIF2AK2 Polyclonal Antibody
- SKU:
- CAB4047
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | PKR/EIF2AK2 Polyclonal Antibody |
| Product Code: | CAB4047 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:2000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | A-549 |
| Cellular Location: | Cytoplasm, Nucleus, perinuclear region |
| Customer Validation: | WB(Homo sapiens) IF(Homo sapiens) |
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PKR/EIF2AK2 (NP_002750.1). |
| Sequence: | MAGDL SAGFF MEELN TYRQK QGVVL KYQEL PNSGP PHDRR FTFQV IIDGR EFPEG EGRSK KEAKN AAAKL AVEIL NKEKK AVSPL LLTTT NSSEG LSMGN YIGLI NRIAQ KKRLT VNYEQ CASGV HGPEG FHYKC KMGQK EYSIG TGSTK QEAKQ LAAKL AYLQI LSEET SVKSD YLSSG SFATT CESQS NSLVT STLAS ESSSE GDFSA DTSEI NSNSD SLNSS SLLMN GLRNN QRKAK RSLAP RFDLP DMKET KYTVD KRFGM DFKEI |
| Synonyms: | PKR, PRKR, DYT33, LEUDEN, EIF2AK1, PPP1R83 |
| Calculated MW: | 62kDa |
| Observed MW: | 72kDa |
Related Products
Anti-Phospho-PKR/EIF2AK2-T446 Antibody (CABP1251)
OverviewProduct Name:Phospho-PKR/EIF2AK2-T446 Rabbit pAbProduct Code:CABP1251Size:50uL, 100uLSynonyms:EIF2AK1, PKR, PPP1R83, PRKR</
Human PKR / EIF2AK2 ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
