PKN3 Antibody (PACO62763)
- SKU:
- PACO62763
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PKN3 Antibody (PACO62763) |
| Antibody SKU: | PACO62763 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Serine/threonine-protein kinase N3 protein (1-252AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Hela whole cell lysate, PC3 whole cell lysate. All lanes: PKN3 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 100 kDa. Observed band size: 100 kDa. |
 | IHC image of PACO62763 diluted at 1:300 and staining in paraffin-embedded human stomach cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO62763 diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Contributes to invasiveness in malignant prostate cancer. |
| Synonyms: | Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN-beta) (Protein-kinase C-related kinase 3), PKN3, PKNBETA |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6P5Z2 |
| NCBI GenInfo Identifier: | 74749130 |
| NCBI Gene ID: | 29941 |
| NCBI Accession: | Q6P5Z2.1 |
| UniProt Secondary Accession: | Q6P5Z2,Q9UM03 |
| UniProt Related Accession: | Q6P5Z2 |
| Molecular Weight: | 889 |
| NCBI Full Name: | Serine/threonine-protein kinase N3 |
| NCBI Synonym Full Names: | protein kinase N3 |
| NCBI Official Symbol: | PKN3 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | serine/threonine-protein kinase N3; protein kinase PKN-beta; protein-kinase C-related kinase 3 |
| UniProt Protein Name: | Serine/threonine-protein kinase N3 |
| UniProt Synonym Protein Names: | Protein kinase PKN-beta; Protein-kinase C-related kinase 3 |
| Protein Family: | Serine/threonine-protein kinase |
| UniProt Gene Name: | PKN3 |
| UniProt Entry Name: | PKN3_HUMAN |
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