Description
system_update_alt Datasheet
Product Name: | PKLR Antibody |
Product Sku: | CPAB0111 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human PKLR mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PKLR amino acids 47-574 purified from Ecoli. |
Clone: | PPKLRAT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | PKLR antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG1 |
Background: | PKLR is a pyruvate kinase which catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP. That is the rate-limiting step of glycolysis. PKLR gene encodes the L- and R-type isoenzymes through alternate splicing events controlled by different promoters. L-type isoform can also appear as a tetramer and is upregulated by glucose with implications in maturity-onset diabetes of the young. |
Synonyms: | PK1, PKL, RPK, pyruvate kinase isozyme R/L, Red cell/liver pyruvate kinase, PKRL. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |