Description
| Antibody Name: | PKIG Antibody (PACO11270) |
| Antibody SKU: | PACO11270 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human PKIG |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | protein kinase (cAMP-dependent, catalytic) inhibitor gamma;PKIG;MGC126458;MGC126459 ; |
| UniProt Protein Function: | PKIG: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family. |
| UniProt Protein Details: | Protein type:Inhibitor; Protein kinase, regulatory subunit Chromosomal Location of Human Ortholog: 20q12-q13.1 Cellular Component: cytoplasm; nucleus Molecular Function:cAMP-dependent protein kinase inhibitor activity Biological Process: negative regulation of protein import into nucleus; negative regulation of transcription from RNA polymerase II promoter; signal transduction |
| NCBI Summary: | This gene encodes a member of the protein kinase inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive cAMP-dependent protein kinase inhibitor, and is a predominant form of inhibitor in various tissues. The encoded protein may be involved in osteogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9Y2B9 |
| NCBI GenInfo Identifier: | 74355324 |
| NCBI Gene ID: | 11142 |
| NCBI Accession: | AAI04257.1 |
| UniProt Related Accession: | Q9Y2B9 |
| Molecular Weight: | 7,910 Da |
| NCBI Full Name: | Protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| NCBI Synonym Full Names: | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| NCBI Official Symbol: | PKIG |
| NCBI Official Synonym Symbols: | PKI-gamma |
| NCBI Protein Information: | cAMP-dependent protein kinase inhibitor gamma |
| UniProt Protein Name: | cAMP-dependent protein kinase inhibitor gamma |
| Protein Family: | cAMP-dependent protein kinase |
| UniProt Gene Name: | PKIG |
| UniProt Entry Name: | IPKG_HUMAN |