PKIB Antibody (PACO51122)
- SKU:
- PACO51122
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PKIB Antibody (PACO51122) |
| Antibody SKU: | PACO51122 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human cAMP-dependent protein kinase inhibitor β protein (1-77AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO51122 at dilution of 1:100. |
 | Immunofluorescent analysis of MCF-7 cells using PACO51122 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO51122 at dilution of 1:100. |
| Background: | Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. |
| Synonyms: | cAMP-dependent protein kinase inhibitor β (PKI-beta), PKIB, PRKACN2 |
| UniProt Protein Function: | PKIB: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family. |
| UniProt Protein Details: | Protein type:Protein kinase, regulatory subunit; Inhibitor Chromosomal Location of Human Ortholog: 6q22.31 Cellular Component: cytoplasm; nucleus Molecular Function:cAMP-dependent protein kinase inhibitor activity |
| NCBI Summary: | This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
| UniProt Code: | Q9C010 |
| NCBI GenInfo Identifier: | 17378640 |
| NCBI Gene ID: | 5570 |
| NCBI Accession: | Q9C010.1 |
| UniProt Secondary Accession: | Q9C010,Q567T9, Q5T0Z7, B2RCK2, |
| UniProt Related Accession: | Q9C010 |
| Molecular Weight: | 9,237 Da |
| NCBI Full Name: | cAMP-dependent protein kinase inhibitor beta |
| NCBI Synonym Full Names: | protein kinase (cAMP-dependent, catalytic) inhibitor beta |
| NCBI Official Symbol: | PKIB |
| NCBI Official Synonym Symbols: | PRKACN2 |
| NCBI Protein Information: | cAMP-dependent protein kinase inhibitor beta; PKI-beta; cAMP-dependent protein kinase inhibitor 2 |
| UniProt Protein Name: | cAMP-dependent protein kinase inhibitor beta |
| Protein Family: | cAMP-dependent protein kinase |
| UniProt Gene Name: | PKIB |
| UniProt Entry Name: | IPKB_HUMAN |
| Antibodies | ELISA Kits |
| PKIB Antibody (PACO04712) | Human PKI beta (Protein Kinase Inhibitor Beta) ELISA Kit (HUES02266) |
| PKIB Antibody (PACO11269) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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system_update_altDatasheetHuman PKIB/PKI-Beta Recombinant Protein cAMP-Dependent Protein Kinase Inhibitor β (PKI-β) is a member of the PKI family. As a member of the cAMP-dependent prot