Description
| Antibody Name: | PKIB Antibody (PACO11269) |
| Antibody SKU: | PACO11269 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human PKIB |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | protein kinase (cAMP-dependent, catalytic) inhibitor beta;PKIB;FLJ23817;PRKACN2 ; |
| UniProt Protein Function: | PKIB: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family. |
| UniProt Protein Details: | Protein type:Protein kinase, regulatory subunit; Inhibitor Chromosomal Location of Human Ortholog: 6q22.31 Cellular Component: cytoplasm; nucleus Molecular Function:cAMP-dependent protein kinase inhibitor activity |
| NCBI Summary: | This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
| UniProt Code: | Q9C010 |
| NCBI GenInfo Identifier: | 17378640 |
| NCBI Gene ID: | 5570 |
| NCBI Accession: | Q9C010.1 |
| UniProt Secondary Accession: | Q9C010,Q567T9, Q5T0Z7, B2RCK2, |
| UniProt Related Accession: | Q9C010 |
| Molecular Weight: | 9,237 Da |
| NCBI Full Name: | cAMP-dependent protein kinase inhibitor beta |
| NCBI Synonym Full Names: | protein kinase (cAMP-dependent, catalytic) inhibitor beta |
| NCBI Official Symbol: | PKIB |
| NCBI Official Synonym Symbols: | PRKACN2 |
| NCBI Protein Information: | cAMP-dependent protein kinase inhibitor beta; PKI-beta; cAMP-dependent protein kinase inhibitor 2 |
| UniProt Protein Name: | cAMP-dependent protein kinase inhibitor beta |
| Protein Family: | cAMP-dependent protein kinase |
| UniProt Gene Name: | PKIB |
| UniProt Entry Name: | IPKB_HUMAN |