PKIA Antibody (PACO23239)
- SKU:
- PACO23239
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PKIA Antibody (PACO23239) |
| Antibody SKU: | PACO23239 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100, IF:1:100-1:500 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human IPKA. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TPD52 antibody. |
 | Immunofluorescence analysis of HeLa cells, using TPD52 antibody. |
| Background: | Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. |
| Synonyms: | IPKA; OKRBCI; PKI-alpha; PRKACN1; cAMP-dependent protein kinase inhibitor alpha |
| UniProt Protein Function: | PKIA: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. Belongs to the PKI family. |
| UniProt Protein Details: | Protein type:Inhibitor Chromosomal Location of Human Ortholog: 8q21.13 Cellular Component: cytoplasm; nucleus Molecular Function:cAMP-dependent protein kinase inhibitor activity; protein binding Biological Process: negative regulation of cAMP-dependent protein kinase activity; negative regulation of protein import into nucleus; negative regulation of transcription from RNA polymerase II promoter; regulation of G2/M transition of mitotic cell cycle |
| NCBI Summary: | The protein encoded by this gene is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P61925 |
| NCBI GenInfo Identifier: | 5803127 |
| NCBI Gene ID: | 5569 |
| NCBI Accession: | NP_006814.1 |
| UniProt Secondary Accession: | P61925,P04541, Q6IAV2, |
| UniProt Related Accession: | P61925 |
| Molecular Weight: | |
| NCBI Full Name: | cAMP-dependent protein kinase inhibitor alpha |
| NCBI Synonym Full Names: | cAMP-dependent protein kinase inhibitor alpha |
| NCBI Official Symbol: | PKIA |
| NCBI Official Synonym Symbols: | PRKACN1 |
| NCBI Protein Information: | cAMP-dependent protein kinase inhibitor alpha |
| UniProt Protein Name: | cAMP-dependent protein kinase inhibitor alpha |
| UniProt Synonym Protein Names: | cAMP-dependent protein kinase inhibitor, muscle/brain isoform |
| Protein Family: | Protein |
| UniProt Gene Name: | PKIA |
| Antibodies | ELISA Kits |
| PKIA Antibody (PACO04711) | Human PKI alpha (Protein Kinase Inhibitor Alpha) ELISA Kit (HUES02265) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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