PKD2L1 Antibody (PACO18349)
- SKU:
- PACO18349
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PKD2L1 Antibody (PACO18349) |
| Antibody SKU: | PACO18349 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:20-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human PKD2L1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18349(PKD2L1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two transcript variants encoding different isoforms have been found for this gene. |
| Synonyms: | polycystic kidney disease 2-like 1 |
| UniProt Protein Function: | PKD2L1: May function as a subunit of an ion channel and act as a transducer of calcium-mediated signaling. Belongs to the polycystin family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integral; Motility/polarity/chemotaxis; Channel, cationChromosomal Location of Human Ortholog: 10q24Cellular Component: cell surface; endoplasmic reticulum; intracellular membrane-bound organelle; membrane; nonmotile primary cilium; plasma membrane; receptor complexMolecular Function: alpha-actinin binding; calcium activated cation channel activity; calcium channel activity; calcium ion binding; calcium-activated potassium channel activity; cation channel activity; cation transmembrane transporter activity; cytoskeletal protein binding; identical protein binding; muscle alpha-actinin binding; protein binding; sodium channel activity; sour taste receptor activityBiological Process: cation transport; detection of chemical stimulus involved in sensory perception of sour taste; detection of mechanical stimulus; sensory perception of sour taste; smoothened signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| UniProt Code: | Q9P0L9 |
| NCBI GenInfo Identifier: | 23821938 |
| NCBI Gene ID: | 9033 |
| NCBI Accession: | Q9P0L9.1 |
| UniProt Secondary Accession: | Q9P0L9,O75972, Q5W039, Q9UP35, Q9UPA2 |
| UniProt Related Accession: | Q9P0L9 |
| Molecular Weight: | 88,472 Da |
| NCBI Full Name: | Polycystic kidney disease 2-like 1 protein |
| NCBI Synonym Full Names: | polycystin 2 like 1, transient receptor potential cation channel |
| NCBI Official Symbol: | PKD2L1 |
| NCBI Official Synonym Symbols: | PCL; PKDL; PKD2L; TRPP3 |
| NCBI Protein Information: | polycystic kidney disease 2-like 1 protein |
| UniProt Protein Name: | Polycystic kidney disease 2-like 1 protein |
| UniProt Synonym Protein Names: | Polycystin-2 homolog; Polycystin-2L1; Polycystin-L; Polycystin-L1 |
| Protein Family: | Polycystic kidney disease 2-like 1 protein |
| UniProt Gene Name: | PKD2L1 |
| UniProt Entry Name: | PK2L1_HUMAN |
| Antibodies |
| PKD2L1 Antibody (PACO11268) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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