PKD1L3 Antibody (PACO47974)
- SKU:
- PACO47974
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PKD1L3 Antibody (PACO47974) |
| Antibody SKU: | PACO47974 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Polycystic kidney disease protein 1-like 3 protein (22-194AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO47974 at dilution of 1:100. |
 | Immunofluorescent analysis of A549 cells using PACO47974 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human heart tissue using PACO47974 at dilution of 1:100. |
| Background: | Component of a calcium channel. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect. |
| Synonyms: | Polycystic kidney disease protein 1-like 3 (PC1-like 3 protein) (Polycystin-1L3), PKD1L3 |
| UniProt Protein Function: | PKD1L3: May function as an ion-channel regulator. May function with PKD2L1 as heteromeric taste channels. Belongs to the polycystin family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 16q22.2Cellular Component: cell surface; plasma membrane; receptor complexMolecular Function: calcium channel activity; cation channel activity; cation transmembrane transporter activity; protein binding; sour taste receptor activityBiological Process: cation transport; detection of chemical stimulus involved in sensory perception of sour taste; detection of mechanical stimulus; sensory perception of sour taste |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores.[provided by RefSeq, Apr 2009] |
| UniProt Code: | Q7Z443 |
| NCBI GenInfo Identifier: | 31559825 |
| NCBI Gene ID: | 342372 |
| NCBI Accession: | NP_853514.1 |
| UniProt Secondary Accession: | Q7Z443 |
| UniProt Related Accession: | Q7Z443 |
| Molecular Weight: | 195,894 Da |
| NCBI Full Name: | polycystic kidney disease protein 1-like 3 |
| NCBI Synonym Full Names: | polycystin 1 like 3, transient receptor potential channel interacting |
| NCBI Official Symbol: | PKD1L3 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | polycystic kidney disease protein 1-like 3 |
| UniProt Protein Name: | Polycystic kidney disease protein 1-like 3 |
| UniProt Synonym Protein Names: | PC1-like 3 protein; Polycystin-1L3 |
| Protein Family: | Polycystic kidney disease protein |
| UniProt Gene Name: | PKD1L3 |
| UniProt Entry Name: | PK1L3_HUMAN |
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