PKC alpha Monoclonal Antibody (CAB23231)

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SKU:
CAB23231
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IF

Description

Product Name:PKC alpha Monoclonal Antibody
Product Code:CAB23231
Reactivity:Human, Mouse, Rat
Applications:Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC58845
Reactivity:Human, Mouse, Rat
Tested Applications:IF/ICC, ELISA
Key Applications:Immunofluorescence
Recommended Dilution:IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Cellular Location:Cell membrane, Cytoplasm, Mitochondrion membrane, Nucleus, Peripheral membrane protein

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Immunogen:Recombinant protein of human PKC alpha.
Sequence:Email for sequence
Synonyms:AAG6, PKCA, PRKACA, PKCI+/-, PKCalpha, PKC-alpha
Calculated MW:77kDa
Observed MW:Refer to figures
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