Description
| Product Name: | PKA C-beta (PRKACB) Monoclonal Antibody |
| Product Code: | CAB22721 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57124 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:20000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, Mouse brain, Rat brain, Rat testis |
| Cellular Location: | Cell membrane, Cytoplasm, Lipid-anchor, Membrane, Nucleus |
The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 251-351 of human PKA C-beta (PRKACB). |
| Sequence: | IVSGK VRFPS HFSSD LKDLL RNLLQ VDLTK RFGNL KNGVS DIKTH KWFAT TDWIA IYQRK VEAPF IPKFR GSGDT SNFDD YEEED IRVSI TEKCA KEFGE F |
| Synonyms: | CAFD2 |
| Calculated MW: | 41kDa |
| Observed MW: | 39-41kDa |