PITRM1 Monoclonal Antibody
- SKU:
- CAB24652
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | PITRM1 Monoclonal Antibody |
| Product Code: | CAB24652 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63553 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:100-1:500, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse placenta |
| Cellular Location: | Mitochondrion matrix |
The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 758-1037 of human PITRM1 (NP_055704.2). |
| Sequence: | IKPIL RKLPR IKKHL LNGDN MRCSV NATPQ QMPQT EKAVE DFLRS IGRSK KERRP VRPHT VEKPV PSSSG GDAHV PHGSQ VIRKL VMEPT FKPWQ MKTHF LMPFP VNYVG ECIRT VPYTD PDHAS LKILA RLMTA KFLHT EIREK GGAYG GGAKL SHNGI FTLYS YRDPN TIETL QSFGK AVDWA KSGKF TQQDI DEAKL SVFST VDAPV APSDK GMDHF LYGLS DEMKQ AHREQ LFAVS HDKLL AVSDR YLGTG KSTHG LAILG PENPK IAKDP SWIIQ |
| Synonyms: | MP1, PreP, SCAR30 |
| Calculated MW: | 117kDa |
| Observed MW: | 117kDa |
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