PIK3CA Polyclonal Antibody

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SKU:
CAB21746
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:PIK3CA Polyclonal Antibody
Product Code:CAB21746
Reactivity:Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:2000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:Mouse lung, Mouse brain, Rat brain
Cellular Location:cytoplasm, cytosol, intercalated disc, perinuclear region of cytoplasm, plasma membrane

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4, 5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human PIK3CA (NP_006209.2).
Sequence:DCFTM PSYSR RISTA TPYMN GETST KSLWV INSAL RIKIL CATYV NVNIR DIDKI YVRTG IYHGG EPLCD NVNTQ RVPCS NPRWN EWLNY DIYIP DLPRA ARLCL SICSV KGRKG AKEEH CPLAW GNINL FDYTD TLVSG KMALN LWPVP HGLED LLNPI GVTGS NPNKE TPCLE LEFDW FSSVV KFPDM SVIEE HANWS VSREA GFSYS HAGLS NRLAR DNELR ENDKE QLKAI STRDP LSEIT EQEKD FLWSH RHYCV TIPEI LPKLL LSVKW NSRDE VAQMY CLVKD WPPIK PEQAM E
Synonyms:MCM, CCM4, CWS5, MCAP, PI3K, CLAPO, CLOVE, MCMTC, PI3K-alpha, p110-alpha
Calculated MW:124kDa
Observed MW:112kDa
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