PIK3C2G Antibody (PACO07210)
- SKU:
- PACO07210
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PIK3C2G Antibody (PACO07210) |
| Antibody SKU: | PACO07210 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from the N-terminal region of human PI 3-Kinase C2 γ . |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of A549 using PI 3-Kinase C2 gamma antibody. Secondary antibody was diluted at 1:20000. |
| Synonyms: | PIK3C2G; Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit γ; PI3K-C2-γ; PtdIns-3-kinase C2 subunit γ; Phosphoinositide 3-kinase-C2-γ |
| UniProt Protein Function: | PIK3C2G: Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers. May play a role in SDF1A-stimulated chemotaxis. Belongs to the PI3/PI4-kinase family.Protein type: Kinase, lipid; EC 2.7.1.154; Motility/polarity/chemotaxis; Carbohydrate Metabolism - inositol phosphateChromosomal Location of Human Ortholog: 12p12Cellular Component: cytosol; phosphoinositide 3-kinase complex; plasma membraneMolecular Function: 1-phosphatidylinositol-3-kinase activity; phosphatidylinositol-4-phosphate 3-kinase activityBiological Process: phosphatidylinositol biosynthetic process |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| UniProt Code: | O75747 |
| NCBI GenInfo Identifier: | 313104205 |
| NCBI Gene ID: | 5288 |
| NCBI Accession: | O75747.3 |
| UniProt Secondary Accession: | O75747,A1L3U0 |
| UniProt Related Accession: | O75747 |
| Molecular Weight: | 165,715 Da |
| NCBI Full Name: | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma |
| NCBI Synonym Full Names: | phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma |
| NCBI Official Symbol: | PIK3C2G |
| NCBI Official Synonym Symbols: | PI3K-C2GAMMA; PI3K-C2-gamma |
| NCBI Protein Information: | phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma |
| UniProt Protein Name: | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma |
| UniProt Synonym Protein Names: | Phosphoinositide 3-kinase-C2-gamma |
| Protein Family: | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing |
| UniProt Gene Name: | PIK3C2G |
| UniProt Entry Name: | P3C2G_HUMAN |
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