Name: PIGS Antibody (PACO39362)
SKU: PACO39362
Availability: OutOfStock

Antibody Name:	PIGS Antibody (PACO39362)
Antibody SKU:	PACO39362
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:	Human
Immunogen:	Recombinant Human GPI transamidase component PIG-S protein (40-300AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Immunofluorescent analysis of HepG2 cells using PACO39362 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Background:	Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates.
Synonyms:	GPI transamidase component PIG-S (Phosphatidylinositol-glycan biosynthesis class S protein), PIGS

UniProt Protein Function:	PIGS: Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates. Belongs to the PIGS family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, multi-passChromosomal Location of Human Ortholog: 17p13.2Cellular Component: endoplasmic reticulum membrane; GPI-anchor transamidase complex; membraneMolecular Function: GPI-anchor transamidase activity; protein bindingBiological Process: attachment of GPI anchor to protein
UniProt Protein Details:
NCBI Summary:	This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq, Jul 2008]
UniProt Code:	Q96S52
NCBI GenInfo Identifier:	21759353
NCBI Gene ID:	94005
NCBI Accession:	Q96S52.3
UniProt Secondary Accession:	Q96S52,Q6UVX6
UniProt Related Accession:	Q96S52
Molecular Weight:	61,005 Da
NCBI Full Name:	GPI transamidase component PIG-S
NCBI Synonym Full Names:	phosphatidylinositol glycan anchor biosynthesis class S
NCBI Official Symbol:	PIGS
NCBI Official Synonym Symbols:
NCBI Protein Information:	GPI transamidase component PIG-S
UniProt Protein Name:	GPI transamidase component PIG-S
UniProt Synonym Protein Names:	Phosphatidylinositol-glycan biosynthesis class S protein
Protein Family:	GPI transamidase component
UniProt Gene Name:	PIGS
UniProt Entry Name:	PIGS_HUMAN