PIGC Antibody (PACO40050)
- SKU:
- PACO40050
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PIGC Antibody (PACO40050) |
| Antibody SKU: | PACO40050 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Phosphatidylinositol N-acetylglucosaminyltransferase subunit C protein (1-50AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of PC-3 cells using PACO40050 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. |
| Synonyms: | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C (EC 2.4.1.198) (Phosphatidylinositol-glycan biosynthesis class C protein) (PIG-C), PIGC, GPI2 |
| UniProt Protein Function: | PIGC: Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. Belongs to the PIGC family.Protein type: Endoplasmic reticulum; Membrane protein, multi-pass; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Transferase; Membrane protein, integral; EC 2.4.1.198Chromosomal Location of Human Ortholog: 1q23-q25Cellular Component: endoplasmic reticulum membrane; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complexMolecular Function: catalytic activityBiological Process: GPI anchor biosynthetic process; preassembly of GPI anchor in ER membrane |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q92535 |
| NCBI GenInfo Identifier: | 14916629 |
| NCBI Gene ID: | 5279 |
| NCBI Accession: | Q92535.1 |
| UniProt Secondary Accession: | Q92535,O14491 |
| UniProt Related Accession: | Q92535 |
| Molecular Weight: | 33,583 Da |
| NCBI Full Name: | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C |
| NCBI Synonym Full Names: | phosphatidylinositol glycan anchor biosynthesis class C |
| NCBI Official Symbol: | PIGC |
| NCBI Official Synonym Symbols: | GPI2 |
| NCBI Protein Information: | phosphatidylinositol N-acetylglucosaminyltransferase subunit C |
| UniProt Protein Name: | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C |
| UniProt Synonym Protein Names: | Phosphatidylinositol-glycan biosynthesis class C protein; PIG-C |
| Protein Family: | Prodigiosin synthesizing transferase |
| UniProt Gene Name: | PIGC |
| UniProt Entry Name: | PIGC_HUMAN |
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