Description
| Antibody Name: | PIGB Antibody (PACO11237) |
| Antibody SKU: | PACO11237 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human PIGB |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | phosphatidylinositol glycan anchor biosynthesis, class B;PIGB;MGC21236 ; |
| UniProt Protein Function: | PIGB: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly. Belongs to the glycosyltransferase 22 family. PIGB subfamily.Protein type: Membrane protein, integral; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Transferase; Membrane protein, multi-pass; Endoplasmic reticulum; EC 2.4.1.-Chromosomal Location of Human Ortholog: 15q21.3Cellular Component: endoplasmic reticulum membrane; integral to membraneMolecular Function: mannosyltransferase activityBiological Process: cellular protein metabolic process; preassembly of GPI anchor in ER membrane; GPI anchor biosynthetic process; C-terminal protein lipidation; post-translational protein modification |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q92521 |
| NCBI GenInfo Identifier: | 110224465 |
| NCBI Gene ID: | 9488 |
| NCBI Accession: | NP_004846.4 |
| UniProt Secondary Accession: | Q92521,Q53FF9, Q8WVN7 |
| UniProt Related Accession: | Q92521 |
| Molecular Weight: | 65056 |
| NCBI Full Name: | GPI mannosyltransferase 3 |
| NCBI Synonym Full Names: | phosphatidylinositol glycan anchor biosynthesis, class B |
| NCBI Official Symbol: | PIGB |
| NCBI Official Synonym Symbols: | PIG-B; GPI-MT-III |
| NCBI Protein Information: | GPI mannosyltransferase 3 |
| UniProt Protein Name: | GPI mannosyltransferase 3 |
| UniProt Synonym Protein Names: | GPI mannosyltransferase III; GPI-MT-III; Phosphatidylinositol-glycan biosynthesis class B protein; PIG-B |
| Protein Family: | Oxidoreductase |
| UniProt Gene Name: | PIGB |
| UniProt Entry Name: | PIGB_HUMAN |