PI3 Kinase p85 alpha/beta/gamma Monoclonal Antibody

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SKU:
CAB22996
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IF

Description

Product Name:PI3 Kinase p85 alpha/beta/gamma Monoclonal Antibody
Product Code:CAB22996
Reactivity:Mouse, Rat
Applications:Western blotting, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC57209
Reactivity:Mouse, Rat
Tested Applications:WB, IF/ICC, ELISA
Key Applications:Western blotting, Immunofluorescence
Recommended Dilution:WB 1:2000-1:10000, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Mouse brain
Cellular Location:Golgi network, Cytoplasm, Cytosol, Nucleus, Perinuclear region of cytoplasm, Plasma membrane

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 400-500 of human PI3 Kinase p85 alpha/beta (NP_852664.1).
Sequence:SVVEL INHYR NESLA QYNPK LDVKL LYPVS KYQQD QVVKE DNIEA VGKKL HEYNT QFQEK SREYD RLYEE YTRTS QEIQM KRTAI EAFNE TIKIF EEQCQ T
Synonyms:PIK3R1/PIK3R2/PIK3R3
Calculated MW:42-54kDa/81-84kDa
Observed MW:85kDa
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