Description
Product Name: | PI3 Kinase p110 beta Monoclonal Antibody |
Product Code: | CAB22467 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC54484 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:1000-1:5000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | K-562, 293F, Mouse brain, Mouse placenta, Rat brain, Rat lung |
Cellular Location: | Cytoplasm, Nucleus |
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 410-600 of human PI3 Kinase p110 beta (NP_006210.1). |
Sequence: | KVKTK KSTKT INPSK YQTIR KAGKV HYPVA WVNTM VFDFK GQLRT GDIIL HSWSS FPDEL EEMLN PMGTV QTNPY TENAT ALHVK FPENK KQPYY YPPFD KIIEK AAEIA SSDSA NVSSR GGKKF LPVLK EILDR DPLSQ LCENE MDLIW TLRQD CREIF PQSLP KLLLS IKWNK LEDVA QLQAL LQIWP K |
Synonyms: | PI3K, PIK3C1, P110BETA, PI3KBETA |
Calculated MW: | 123kDa |
Observed MW: | 123kDa |