Description
Product Name: | PI3 Kinase p110 alpha Monoclonal Antibody |
Product Code: | CAB22730 |
Reactivity: | Human, Mouse |
Applications: | Western blotting, Immunoprecipitation |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC58257 |
Reactivity: | Human, Mouse |
Tested Applications: | WB, IP, ELISA |
Key Applications: | Western blotting, Immunoprecipitation |
Recommended Dilution: | WB 1:10000-1:90000, IP 1:10000-1:90000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Jurkat, MCF7, NIH/3T3, Mouse brain |
Cellular Location: | Cytoplasm, Cytosol, plasma membrane |
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4, 5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.
Immunogen: | Recombinant protein of human PI3 Kinase p110 alpha. |
Sequence: | Email for sequence |
Synonyms: | MCM, CCM4, CWS5, MCAP, PI3K, CLAPO, CLOVE, MCMTC, PI3K-alpha, p110-alpha |
Calculated MW: | 124kDa |
Observed MW: | 110kDa |