PHYKPL Antibody (PACO15355)
- SKU:
- PACO15355
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | PHYKPL Antibody (PACO15355) |
| Antibody SKU: | PACO15355 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human AGXT2L2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human lymphoma tissue, Primary antibody: PACO15355(AGXT2L2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. |
| Background: | This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. |
| Synonyms: | 5-phosphohydroxy-L-lysine phospho-lyase |
| UniProt Protein Function: | AGXT2L2: Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 4.2.3.134; TransferaseChromosomal Location of Human Ortholog: 5q35.3Cellular Component: mitochondrial matrixMolecular Function: identical protein binding; lyase activity; protein binding; pyridoxal phosphate binding; transaminase activityBiological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; lysine catabolic processDisease: Phosphohydroxylysinuria |
| UniProt Protein Details: | |
| NCBI Summary: | This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
| UniProt Code: | Q8IUZ5 |
| NCBI GenInfo Identifier: | 74750645 |
| NCBI Gene ID: | 85007 |
| NCBI Accession: | Q8IUZ5.1 |
| UniProt Secondary Accession: | Q8IUZ5,Q8WYS6, Q96HW8, A8K7P6, B3KN36, D3DWP9 |
| UniProt Related Accession: | Q8IUZ5 |
| Molecular Weight: | 18,857 Da |
| NCBI Full Name: | 5-phosphohydroxy-L-lysine phospho-lyase |
| NCBI Synonym Full Names: | 5-phosphohydroxy-L-lysine phospho-lyase |
| NCBI Official Symbol: | PHYKPL |
| NCBI Official Synonym Symbols: | PHLU; AGXT2L2 |
| NCBI Protein Information: | 5-phosphohydroxy-L-lysine phospho-lyase |
| UniProt Protein Name: | 5-phosphohydroxy-L-lysine phospho-lyase |
| UniProt Synonym Protein Names: | Alanine--glyoxylate aminotransferase 2-like 2 |
| Protein Family: | |
| UniProt Gene Name: | PHYKPL |
| UniProt Entry Name: | AT2L2_HUMAN |
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