Description
Product Name: | Phospho-YAP1-S127 Monoclonal Antibody |
Product Code: | CABP1436 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC61727 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:1000-1:5000, IF 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HeLa Calyculin A,C6 CalycμLin A |
Cellular Location: | Cytoplasm, Nucleus |
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen: | A synthetic phosphorylated peptide around S127 of human YAP1(NP_001123617.1). |
Sequence: | RAHSS P |
Synonyms: | YAP1, COB1, YAP, YAP2, YAP65, YKI, Yes associated protein 1 |
Calculated MW: | 36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa |
Observed MW: | 75kDa |