Phospho-TBK1/NAK-S172 Monoclonal Antibody

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SKU:
CABP1418
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:Phospho-TBK1/NAK-S172 Monoclonal Antibody
Product Code:CABP1418
Reactivity:Human, Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC57906
Reactivity:Human, Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:100-1:500
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:NIH/3T3
Cellular Location:Cytoplasm
Customer Validation:WB(Mus musculus)

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein is also an important kinase for antiviral innate immunity response.

Immunogen:A phospho synthetic peptide corresponding to residues surrounding S172 of Human TBK1/NAK.
Sequence:Email for sequence
Synonyms:NAK, T2K, IIAE8, FTDALS4
Calculated MW:84kDa
Observed MW:84kDa
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