Phospho-Stat5a/Stat5b (Ser725/730) Antibody (PACO24063)
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- SKU:
- PACO24063
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Phospho-Stat5a/Stat5b (Ser725/730) Antibody (PACO24063) |
| Antibody SKU: | PACO24063 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:1000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Peptide sequence around phosphorylation site of serine725/730(A-P-S(p)-P-V) derived from Human STAT5A/B. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from Jurkat cells treated with EGF using Phospho-STAT5A/B (Ser725/730) antibody.The lane on the right is treated with the antigen-specific peptide. |
| Background: | Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription. |
| Synonyms: | Signal transducer and activator of transcription 5B; STA5B; STAT5; transcription factor STAT5B; |
| UniProt Protein Function: | Carries out a dual Function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation. |
| UniProt Code: | P42230 |
| NCBI GenInfo Identifier: | 1174463 |
| NCBI Gene ID: | 20850 |
| NCBI Accession: | P42230.1 |
| UniProt Related Accession: | P42230 |
| Molecular Weight: | 90,831 Da |
| NCBI Full Name: | Signal transducer and activator of transcription 5A |
| NCBI Synonym Full Names: | signal transducer and activator of transcription 5A |
| NCBI Official Symbol: | Stat5a |
| NCBI Official Synonym Symbols: | STAT5; AA959963 |
| NCBI Protein Information: | signal transducer and activator of transcription 5A |
| UniProt Protein Name: | Signal transducer and activator of transcription 5A |
| UniProt Synonym Protein Names: | Mammary gland factor |
| Protein Family: | Signal transducer and activator of transcription |
| UniProt Gene Name: | Stat5a |
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