Phospho-SRC Family-Y416 Monoclonal Antibody
- SKU:
- CABP1370
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Phospho-SRC Family-Y416 Monoclonal Antibody |
| Product Code: | CABP1370 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57736 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2+TGFβ, NIH/3T3, NIH/3T3+PDGF |
| Cellular Location: | Cell membrane, Cytoplasm, Mitochondrion inner membrane, Nucleus, Cytoskeleton |
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
| Immunogen: | A synthetic phosphorylated peptide around Y416 of human SRC Family (NP_005408.1). |
| Sequence: | NEYTA R |
| Synonyms: | ASV, SRC1, THC6, c-SRC, p60-Src, SRC |
| Calculated MW: | 60kDa |
| Observed MW: | 62kDa |
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