Phospho-RIPK1-S166 Monoclonal Antibody
- SKU:
- CABP1448
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Phospho-RIPK1-S166 Monoclonal Antibody |
| Product Code: | CABP1448 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62873 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HT-29 treated by Z-VAD+TNF-α+BV-6 |
| Cellular Location: | Cell membrane, Cytoplasm, Mitochondrion |
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth.
| Immunogen: | A synthetic phosphorylated peptide around S166 of human RIPK1(NP_003795.2). |
| Sequence: | MWSKL N |
| Synonyms: | RIP, RIP1, AIEFL, IMD57, RIP-1 |
| Calculated MW: | 75kDa |
| Observed MW: | 70kDa |
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