Phospho-PIK3R1/PIK3R2/PIK3R3-Y467 Antibody (CABP0427)
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- SKU:
- CABP0427
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Antibody Name: | Phospho-PIK3R1/PIK3R2/PIK3R3-Y467 Antibody (CABP0427) |
| Antibody SKU: | CABP0427 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding Y467 of human PIK3R1/2/3 |
| Application: | Western blotting |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293 |
| Immunogen: | A phospho specific peptide corresponding to residues surrounding Y467 of human PIK3R1/2/3 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Cellular Location: | |
| Calculated MW: | 42-54kDa/81-84kDa |
| Observed MW: | 85kDa |
| Synonyms: | PIK3R1/PIK3R2/PIK3R3 |
| Background: | Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. provided by RefSeq, Jun 2011 |
 | Western blot analysis of extracts from 293 cells, using phospho-PIK3R1/2/3-Y467 antibody . Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA. |
