Phospho-PAK2-S20 Monoclonal Antibody
- SKU:
- CABP1443
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Phospho-PAK2-S20 Monoclonal Antibody |
| Product Code: | CABP1443 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62567 |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | NIH/3T3+CA, C6+CA |
| Cellular Location: | Cytoplasm, Membrane, Nucleus |
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
| Immunogen: | A synthetic phosphorylated peptide around S20 of human PAK2 (NP_002568.2). |
| Sequence: | MSSTI |
| Synonyms: | KNO2, PAK65, PAKgamma |
| Calculated MW: | 58kDa |
| Observed MW: | 61kDa/67kDa |
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