Phospho-PAK2-S20 Monoclonal Antibody

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SKU:
CABP1443
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:Phospho-PAK2-S20 Monoclonal Antibody
Product Code:CABP1443
Reactivity:Mouse, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC62567
Reactivity:Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:1000-1:5000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:NIH/3T3+CA, C6+CA
Cellular Location:Cytoplasm, Membrane, Nucleus

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

Immunogen:A synthetic phosphorylated peptide around S20 of human PAK2 (NP_002568.2).
Sequence:MSSTI
Synonyms:KNO2, PAK65, PAKgamma
Calculated MW:58kDa
Observed MW:61kDa/67kDa
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