Description
Product Name: | Phospho-PAK1-S199/S204 + PAK2-S192/S197 Polyclonal Antibody |
Product Code: | CABP0550 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Immunogen: | A synthetic phosphorylated peptide around S199 & S204 of human PAK1 (NP_002567.3). |
Sequence: | SVYTR S |
Synonyms: | PAK1/PAK2 |
Calculated MW: | 60kDa/61kDa/58kDa |
Observed MW: | Refer to figures |