Phospho-NF-kB p65/RelA-T505 Polyclonal Antibody
- SKU:
- CABP1318
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Phospho-NF-kB p65/RelA-T505 Polyclonal Antibody |
| Product Code: | CABP1318 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | U-2 OS+cisplatin |
| Cellular Location: | cytoplasm, cytosol, glutamatergic synapse, nucleoplasm, nucleus |
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic phosphorylated peptide around T505 of human Phospho-NF-kB p65/RelA-T505 (NP_068810.3). |
| Sequence: | LVTGA |
| Synonyms: | p65, CMCU, NFKB3, AIF3BL3 |
| Calculated MW: | 60kDa |
| Observed MW: | 65kDa |
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