Phospho-MEK1/MEK2-S217/S221 Monoclonal Antibody
- SKU:
- CABP1349
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Phospho-MEK1/MEK2-S217/S221 Monoclonal Antibody |
| Product Code: | CABP1349 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55711 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:10000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa+PMA, NIH/3T3+PMA |
| Cellular Location: | nucleus, membrane, cytoskeleton, microtubule organizing center, spindle pole body, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome |
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
| Immunogen: | A synthetic phosphorylated peptide around S217 & S221 of human MEK1/MEK2 (NP_002746.1). |
| Sequence: | DSMAN |
| Synonyms: | MEK1/MEK2 |
| Calculated MW: | 40kDa/43kDa/44kDa |
| Observed MW: | 42kDa/44kDa |
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