Description
Antibody Name: | Phospho-KCNJ16 (S416) Antibody |
Antibody SKU: | PACO03309 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | synthesized peptide derived from human KIR5.1 around the phosphorylation site of S416. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | KCNJ16; Inward rectifier potassium channel 16; Inward rectifier K(+) channel Kir5.1; Potassium channel; inwardly rectifying subfamily J member 16 |
UniProt Protein Function: | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolateral K+ recycling in distal tubules; this process is critical for Na+ reabsorption at the tubules. |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9Z307 |
NCBI GenInfo Identifier: | 356582281 |
NCBI Gene ID: | 16517 |
NCBI Accession: | NP_001239136.1 |
UniProt Secondary Accession: | Q9Z307,Q8BH37 |
UniProt Related Accession: | Q9Z307 |
Molecular Weight: | 47 kDa |
NCBI Full Name: | inward rectifier potassium channel 16 |
NCBI Synonym Full Names: | potassium inwardly-rectifying channel, subfamily J, member 16 |
NCBI Official Symbol: | Kcnj16 |
NCBI Official Synonym Symbols: | Kir5.1; AI132396; 6430410F18Rik |
NCBI Protein Information: | inward rectifier potassium channel 16 |
UniProt Protein Name: | Inward rectifier potassium channel 16 |
UniProt Synonym Protein Names: | Inward rectifier K(+) channel Kir5.1; Potassium channel, inwardly rectifying subfamily J member 16 |
Protein Family: | |
UniProt Gene Name: | Kcnj16 |
UniProt Entry Name: |