Description
| Product Name: | Phospho-IRS1-S612/S636 Monoclonal Antibody |
| Product Code: | CABP1507 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62071 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | C2C12+insulin |
| Cellular Location: | Caveola, Cytoplasm, Cytosol, Nucleoplasm, Nucleus, Plasma membrane |
This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.
| Immunogen: | A synthetic phosphorylated peptide around S616 of human IRS1(NP_005535.1). |
| Sequence: | DGYMP MS(p) PGVAP V |
| Synonyms: | HIRS-1 |
| Calculated MW: | 132kDa |
| Observed MW: | 180kDa |