Description
Product Name: | Phospho-IRS1-S612/S636 Monoclonal Antibody |
Product Code: | CABP1507 |
Reactivity: | Human, Mouse |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC62071 |
Reactivity: | Human, Mouse |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:100-1:500 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | C2C12+insulin |
Cellular Location: | Caveola, Cytoplasm, Cytosol, Nucleoplasm, Nucleus, Plasma membrane |
This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.
Immunogen: | A synthetic phosphorylated peptide around S616 of human IRS1(NP_005535.1). |
Sequence: | DGYMP MS(p) PGVAP V |
Synonyms: | HIRS-1 |
Calculated MW: | 132kDa |
Observed MW: | 180kDa |