Phospho-IRF3-S396 Monoclonal Antibody

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SKU:
CABP1412
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IF

Description

Product Name:Phospho-IRF3-S396 Monoclonal Antibody
Product Code:CABP1412
Reactivity:Human, Mouse
Applications:Western blotting, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC53831
Reactivity:Human, Mouse
Tested Applications:WB, IF/ICC, ELISA
Key Applications:Western blotting, Immunofluorescence
Recommended Dilution:WB 1:2000-1:24000, IF/ICC 1:100-1:500
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:293T+CA, 293T
Cellular Location:Cytoplasm, Nucleus
Customer Validation:WB(Mus musculus)

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.

Immunogen:A synthetic phosphorylated peptide around S396 of human IRF3 (NP_001562.1).
Sequence:HISNS
Synonyms:IIAE7
Calculated MW:47kDa
Observed MW:45-55kDa
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