Phospho-HDAC4-S632 Monoclonal Antibody

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SKU:
CABP1344
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:Phospho-HDAC4-S632 Monoclonal Antibody
Product Code:CABP1344
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC56258
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:1000-1:5000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Jurkat
Cellular Location:Cytoplasm, Nucleus

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Immunogen:A synthetic phosphorylated peptide around S632 of human Phospho-HDAC4-S632 (NP_006028.2).
Sequence:AQSSP
Synonyms:HD4, AHO3, BDMR, HDACA, HA6116, HDAC-4, HDAC-A, NEDCHF, NEDCHID
Calculated MW:119kDa
Observed MW:100kDa/120kDa
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