Phospho-HDAC4-S246 + HDAC5-S259 + HDAC9-S220 Monoclonal Antibody
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- SKU:
- CABP1394
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | Phospho-HDAC4-S246 + HDAC5-S259 + HDAC9-S220 Monoclonal Antibody |
| Product Code: | CABP1394 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC56536 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T |
| Cellular Location: | cytoplasm, cytosol, histone deacetylase complex, nuclear speck, nucleoplasm, nucleus |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
| Immunogen: | A phospho synthetic peptide corresponding to residues surrounding S246&S259&S220 of Human HDAC4&HDAC5-S259&HDAC9. |
| Sequence: | Email for sequence |
| Synonyms: | HDAC4/HDAC5/HDAC9 |
| Calculated MW: | 57-65kDa/97-122kDa |
| Observed MW: | 124kDa/140kDa |
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